4-[(4-nitrophenyl)methyl]-Pyridine
4-(4-Nitrobenzyl)pyridine
CAS: 1083-48-3
Molecular Formula: C12H10N2O2
4-[(4-nitrophenyl)methyl]-Pyridine - Names and Identifiers
| Name | 4-(4-Nitrobenzyl)pyridine |
| Synonyms | TIMTEC-BB SBB008854 PARA-NITROBENZYLPYRIDINE 4-(4-Nitrobenyl)pyridine 1-(p-Nitrobenzyl)pyridine 4-(p-nitrobenzyl)-pyridin 4-(4-Nitrobenzyl)pyridine 4-[(4-nitrophenyl)methyl]-pyridin 4-[(4-nitrophenyl)methyl]-Pyridine |
| CAS | 1083-48-3 |
| EINECS | 214-108-2 |
| InChI | InChI=1/C12H10N2O2/c15-14(16)12-3-1-10(2-4-12)9-11-5-7-13-8-6-11/h1-8H,9H2 |
4-[(4-nitrophenyl)methyl]-Pyridine - Physico-chemical Properties
| Molecular Formula | C12H10N2O2 |
| Molar Mass | 214.22 |
| Density | 1.2042 (rough estimate) |
| Melting Point | 69-71 °C (lit.) |
| Boling Point | 354.35°C (rough estimate) |
| Flash Point | 185.6°C |
| Water Solubility | Soluble in acetone. Insoluble in water. |
| Vapor Presure | 9.76E-06mmHg at 25°C |
| Appearance | Crystals or Crystalline Powder |
| Color | Light yellow |
| BRN | 170877 |
| pKa | 5.51±0.10(Predicted) |
| Storage Condition | Store below +30°C. |
| Sensitive | Light Sensitive |
| Refractive Index | 1.6660 (estimate) |
| Physical and Chemical Properties | White or light yellow needle-like crystals. Melting Point 72-73 °c. Soluble in ethanol, ether, insoluble in water. |
4-[(4-nitrophenyl)methyl]-Pyridine - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. |
| WGK Germany | 3 |
| RTECS | UT6360000 |
| FLUKA BRAND F CODES | 10-23 |
| TSCA | Yes |
| HS Code | 29333999 |
4-[(4-nitrophenyl)methyl]-Pyridine - Reference Information
| NIST chemical information | information provided by: webbook.nist.gov (external link) |
| EPA chemical substance information | information provided by: ofmpeb.epa.gov (external link) |
| Use | used as acylating agent and alkylating agent in organic synthesis, can also be used for the determination of phosgene and organophosphorus pesticide analysis. The product is toxic and irritating. |
| production method | from the reaction of 4-benzylpyridine nitrate with concentrated sulfuric acid. The two materials were heated together to 50 °c, poured into ice after 5min, and neutralized with ammonia under cooling. It is then extracted with diethyl ether, and the extract is concentrated and crystallized to give the final product in a yield of more than 50%. |
| category | toxic substances |
| toxicity grade | poisoning |
| Acute toxicity | intravenous-mouse LD50: 89 mg/kg |
| flammability hazard characteristics | open flame flammable; High thermal decomposition releases toxic nitrogen oxide smoke |
| storage and transportation characteristics | The warehouse is ventilated and dried at low temperature, separate storage of food additives |
| extinguishing agent | carbon dioxide, foam, sand, water mist. |
Last Update：2024-04-09 21:04:16
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